n South African Gastroenterology Review - Issues in HIV / AIDS and liver disease : review article

Abstract

Kupffer cells, hepatic endothelium and hepatocytes all expressCD4 receptors. Infection by HIV-1 can be demonstratedalthough, to date, HIV infection of cholangiocytes has not beendocumented. In addition HIV associated mRNA and other HIVassociated proteins can readily be found within hepatocytes.