n South African Gastroenterology Review - Cell proliferation and oncogenesis : review
|Article Title||Cell proliferation and oncogenesis : review|
|© Publisher:||In House Publications|
|Journal||South African Gastroenterology Review|
|Publication Date||Nov 2008|
|Pages||15 - 20|
The restriction point (R point) occurs late in G1, but is a critical point where the cell would either pass into S phase and complete the cycle, arrest in the G1 phase or exit into a quiescent G0 phase. It is thought that mutations in the Rb gene, coding for the Rb protein, play a role in neoplastic progression.
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