n South African Gastroenterology Review - World Gastroenterology Organisation Practice Guideline - Hepatitis B September 2008 : guidelines

Volume 7, Issue 1
  • ISSN : 1812-1659



In summary, the outcome of HBV infection largely depends on the host-virus interaction, mediated by the adaptive immune response. The virus-specific T cell response is one of the key factors in the pathogenesis of HBV infection. Viral variants may influence the course and outcome of the disease. The effect of host factors in the progression of disease is underappreciated. Only very rarely (when there is profound immune suppression) does the hepatitis B virus become directly cytopathic.

Loading full text...

Full text loading...


Article metrics loading...


This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error