n South African Gastroenterology Review - Biomarkers in Barrett's oesophagus : review article
|Article Title||Biomarkers in Barrett's oesophagus : review article|
|© Publisher:||In House Publications|
|Journal||South African Gastroenterology Review|
|Publication Date||Mar 2009|
|Pages||10 - 12|
Barrett's oesophagus (BE) is characterized by the replacement of normal stratified squamous epithelium of the distal oesophagus by columnar epithelium with specialized intestinal metaplasia (IM). Intestinal metaplasia in turn is characterized by the presence of goblet cells on histology. It is generally accepted that BE is the only known premalignant condition that precedes the development of oesphageal adenocarcinoma (OAC).There is a strong association with chronic gastroesophageal reflux disease (GERD) and obesity.
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