n African Journal of Psychiatry - A comparison between the efficacy of dydrogesterone and calcium plus vitamin D in improving women's general health : original article
|Article Title||A comparison between the efficacy of dydrogesterone and calcium plus vitamin D in improving women's general health : original article|
|© Publisher:||In House Publications|
|Journal||African Journal of Psychiatry|
|Author||M. Khajehei, K. Abdali and H.R. Tabatabaee|
|Publication Date||Jul 2010|
|Pages||218 - 224|
|Keyword(s)||Calcium plus vitamin D, Dydrogesterone, General health, Shiraz University of Medical Sciences, Shiraz, Iran and Women|
Objective : The aim of this randomized, double-blind, placebo-controlled clinical trial was to evaluate the effect of dydrogesterone and calcium plus vitamin D on young women's general health. Method : One hundred and eighty students studying at Shiraz University were recruited. Students completed the General Health Questionnaires (GHQ-28) prior to participation. They were then randomly assigned to take a tablet containing either 5 mg of dydrogesterone, 500 mg of calcium plus 200 mg of vitamin D, or a placebo twice daily from the 15th to the 24th day of their menstrual cycle for 2 consecutive cycles, and to complete the same questionnaires during both the intervention cycles. Results : The effects of dydrogesterone and calcium plus vitamin D on general health scores were similar during the first month of intervention (11.41±4.28, 12.23±3.76, respectively) (p>0.05) and both of them were more effective than placebo (16.69±3.28) (p<0.05). However, dydrogesterone was more effective than calcium plus vitamin D and placebo during the second month of intervention (4.33±2.69, 6.2±3.55, 14.39±3.45, respectively) (p<0.05). No significant differences between groups regarding drugs' side effects (p>0.05) were found. Conclusion : Both dydrogesterone and calcium D were more effective than placebo in promoting women's general health. Dydrogesterone was, however, more efficient than calcium plus vitamin D.
Article metrics loading...