n African Journal of Psychiatry - Cannabis use predicts shorter duration of untreated psychosis and lower levels of negative symptoms in first-episode psychosis : a South African study : original article
|Article Title||Cannabis use predicts shorter duration of untreated psychosis and lower levels of negative symptoms in first-episode psychosis : a South African study : original article|
|© Publisher:||In House Publications|
|Journal||African Journal of Psychiatry|
|Author||J.K. Burns, K. Jhazbhay and R. Emsley|
|Publication Date||Nov 2010|
|Pages||395 - 399|
|Keyword(s)||Age of onset, Cannabis, Duration of untreated psychosis, First-episode psychosis, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Symptoms and University of Stellenbosch|
Objective : Cannabis use / abuse is a common co-morbid problem in patients experiencing a first episode of psychotic illness (FEP). The relationship between the clinical presentation of FEP and cannabis abuse is complex and warrants further investigation, especially within the South African context. Method : We tested associations between recent / current cannabis use and duration of untreated psychosis (DUP), age of onset (AO), PANSS-rated (Positive and Negative Syndrome Scale) positive, negative and general psychopathology symptoms and depressive symptoms (Calgary Depression Scale for Schizophrenia) in a sample of 54 patients with FEP. Results : Mean DUP was 34.4 weeks, while mean AO was 24.7 years. Co-morbid cannabis use occurred in 35% of the sample and was significantly associated with shorter DUP (Mann-Whitney U, p=0.026). While not significant, there was also a trend association between cannabis use and lower negative symptoms (Mann-Whitney U, p=0.051). Conclusion : Current / recent cannabis use was associated with clinical features of psychosis onset that previously have been associated with better outcome. Medium and long-term outcome for cannabis users however, is likely to depend on whether or not cannabis use is ongoing.
Article metrics loading...