n African Journal of Psychiatry - Mania after termination of epilepsy treatment - a case report : scientific letter




Like many other medical conditions, epilepsy itself increases the risk of psychiatric disorders. Underlying neurological dysfunction due to epilepsy may predispose to psychiatric disorders. There is a similarity between epilepsy and Bipolar Disorder (BD) as they are both episodic, chronic disorders treated with antiepileptic drugs (AEDs) such as valproic acid and carbamazepine (CMZ). However, data on epidemiology and the relationship between epilepsy and mood disorders, is limited to unipolar depression.


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