n Obstetrics and Gynaecology Forum - Spoilt for choice? How to approach the subject of Down's syndrome screening with expecting parents : editorial

Volume 24, Issue 1
  • ISSN : 1027-9148



The risk of Down syndrome (DS; trisomy 21; T21) in the general population is about 1 in 500 in early pregnancy and 1 in 700 amongst live born babies and it is considered standard of care to offer DS screening to all pregnant women. Screening for DS has seen very significant improvements in the last two decades and this has lead to very high expectations from parents, as witnessed by the steep increase in medicolegal claims when a DS baby is born unexpectedly. At present, a plethora of tests is available to determine the risk for DS in an individual pregnancy and the newest test, as discussed in the paper by Urban et al. in this Journal, certainly adds another twist to this story.

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