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oa Southern African Journal of Anaesthesia and Analgesia - Combination proves effective for acute postoperative pain - a meta-analysis of single dose oral tramadol administered in combination with acetaminophen (paracetamol) : product news

 

Abstract

Extracted from text ... 24 Combination proves effective for acute postoperative pain - A meta-analysis of single dose oral tramadol administered in combination with acetaminophen (paracetamol) effect that is greater than either individual component. The combination formulation also had significantly lower NNT (number-needed-to-treat) than the components alone, comparable to ibuprofen (400mg), the gold standard for this pain model. Tramadol alone and acetaminophen (paracetamol) alone had NNT of about 12 and 8, respectively. However, the combination of tramadol and acetaminophen had a much improved NNT of just under 3. Conclusions The meta-analysis demonstrated the analgesic superiority of the combination treatment over its components, without ..

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/content/medsajaa/10/2/EJC73425
2004-05-01
2016-12-08
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