oa Southern African Journal of Anaesthesia and Analgesia - Anaesthesia and ARV : registrar communications and research prize entries



Extracted from text ... REGISTRAR As more and more HIV infected patients gain access to antiretroviral medication, this drug class and its patients have gained particular significance for anaesthetists. This paper offers an overview of antiretrovirals (ARV) with a specific focus on the implications for anaesthetic management. The four main classes of ARV's are as follows: Nucleoside analogue reverse transcriptase inhibitors - zidovudine, didanosine, stavudine; non-nucleoside reverse transcriptase - nevirapine, delavirdine and efavirenz; protease inhibitors - saquinavir, ritonavir, indinavir; fusion inhibitors - enfuvirtide. Common group side effects are looked at in depth. The NRTI's lactic acidosis, pancreatitis, peripheral neuropathies and hepatic failure are ..


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