oa Southern African Journal of Anaesthesia and Analgesia - Novel additives to neuraxial blockade : refresher course



Various drugs have been added to the local anaesthetic agents given intrathecally in an attempt to improve on the analgesic effect of the local anaesthetic agent, as well as the duration of analgesia. They range from the accepted to the bizarre. It is difficult to cover all drugs ever injected intrathecally in a short paper such as this one, particularly if one includes drugs injected intrathecally in animal models and that have as yet not been used in humans.


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