oa Southern African Journal of Anaesthesia and Analgesia - Ketamine : old dogs, new tricks : refresher course
Ketamine is one of the oldest intravenous anaesthetic agents that is still in clinical use. Its unique mechanism of action and interaction with a variety of different receptors has sparked renewed interest in its use in a host of alternative clinical settings. This review briefly discusses the pharmacology of ketamine and ketamine's potential use in major depressive illness, opioidinduced acute tolerance and as a potential neuroprotective agent.
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