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n Medical Technology SA - The identification of a double heterozygote Hb S/β0 thalassaemia in a patient using high performance liquid chromatography (HPLC) : peer reviewed case study

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Abstract

Beta thalassaemia is rare in Africa except for pockets in West Africa, Liberia and Northern Africa whilst sickle cell disease is common in tropical Africa. Hb S/β thalassaemia is a double heterozygous condition occurring in parts of Africa, the Mediterranean - Greece and Italy, the Middle East and in parts of India. We describe a black family from Giyani in the Limpopo Province, South Africa in whom we identified Hb S/β0 thalassaemia in one of the children. Use was made of high performance liquid chromatography (HPLC) technique from Bio-Rad Laboratories, Germany, for the determination of the abnormal haemoglobins. We believe there may be many more such cases seen, due to the enormous influx of people across South Africa's borders.

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/content/medtech/24/1/EJC74234
2010-06-01
2016-12-09
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