n Medical Technology SA - Pathogenesis and future treatments of systemic lupus erythematosus : the role of cytokines and anti-cytokines? : peer reviewed review




Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune connective tissue disorder, which has variable clinical manifestations that range from mild to life-threatening. These can be characterised by multiple organ damage, very high titres of autoantibodies and immune complex deposition. Interestingly the former of these characteristics may precede the clinical manifestations of SLE by many years. It is well recognised that the probable influence of oestrogen hormonal effect in women during childbearing years increases their chances of developing SLE by 10-15 times.


Article metrics loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error