n Medical Technology SA - Peroxidase activity and nuclear density analysis (PANDA ) in the diagnosis of acute promyelocytic leukaemia : peer reviewed short communication




Acute promyelocytic leukaemia (APL) is a subtype of acute myeloid leukaemia (AML), which has both distinct biological and clinical features and is now highly curable. APL was first described by Hillestad in 1957 when he reported three patients, which he characterised by 'a very rapid fatal course of only a few weeks duration', with a white cell blood picture showing promyelocytes in excess and an allied severe bleeding tendency.


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