n Medical Technology SA - Case study : spurious elevation of sodium levels : peer reviewed case study
|Article Title||Case study : spurious elevation of sodium levels : peer reviewed case study|
|© Publisher:||The Society of Medical Laboratory Technologists of South Africa (SMLTSA)|
|Journal||Medical Technology SA|
|Affiliations||1 University of the Free State and 2 University of the Free State|
|Publication Date||Jun 2014|
|Pages||39 - 40|
|Keyword(s)||Intensive care unit (ICU), Ion selective electrode (ISE), Pseudohypernatraemia, Sodium and Spurious result|
In hospitalized patients, plasma sodium disturbances remain common and can be associated with significant mortality and morbidity if not diagnosed and treated. A hypoproteinaemic, critically ill patient with discrepant blood gas analyzer and central laboratory analyzer sodium values presented as a case of possible spurious elevation of sodium or pseudohypernatraemia. The indirect ion selective electrode method yielded a persistently higher sodium value than the direct ion selective electrode method. A statistically significant difference between the sodium measured with the direct ISE and indirect ISE method was noted. The differences could not be explained by analytical variation alone, in most of the samples.
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