n Evidence Based Summaries in Dentistry - The Berger-Exner test for detecting selection bias in randomised controlled trials : summary




Summarised from:

Mickenautsch S, Fu B, Gudehithlu S, Berger VW. Accuracy of the Berger-Exner test for detecting third-order selection bias in randomised controlled trials: a simulation-based investigation. BMC Med Res Methodol 2014, 14:114.

Bias has been defined as systematic error or deviation from the truth in results or inferences. Selection bias is one form of systematic error that interferes with the internal validity of clinical trials and may lead to favouring one treatment group over another. This bias is based on knowledge about patient characteristics that are known to be conducive to successful trial outcomes together with foreknowledge regarding the allocation of such patients in a specific sequence of interventions (i.e., test and control interventions).


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