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n Journal of Minimum Intervention in Dentistry - Caries preventive effect of glass ionomer cement (GIC) - a quantitative systematic review
Objectives To assess whether GIC is more caries preventive than other materials.
Search strategy Trials were identified from a search of the PubMed and LILACS database on 03 March 2008 and 07 April 2008, respectively, using strings of MeSH/text words. References of accepted articles were checked for additional studies suitable for inclusion.
Trial inclusion criteria Relevant to review question; Published in English and Portuguese language.
Trial exclusion criteria Insufficient random allocation of study subjects; Lack of clear accounting for included subjects at the end of the study; Drop-out rate >33%; No in-vivo or In-situ study design.
Data collection and analysis The systematic literature search found 57 trials of which 28 were identified to be in line with the inclusion / exclusion criteria.
Main results Most results indicate no difference between GIC and other materials. This includes no difference in the caries preventive effect of GIC and resin based fissure sealants. Comparison between single-surface restorations in primary teeth indicate a 7% higher likelihood for teeth restored with compomer to remain caries free than with GIC after 3.5 years. Comparison between single-surface restorations in permanent teeth indicate a 102% higher likelihood for teeth restored with GIC to remain caries free than with Amalgam after 6 years. Significantly less mineral loss was observed on bracket-bonded teeth, when GIC was used as compared to composite resin after 1 year.
Conclusions The results indicate a similar, if not higher caries preventive effect of GIC in comparison to other materials. Further high quality trials are needed, as well as more in-depth systematic reviews of such new evidence.
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