n Journal of Minimum Intervention in Dentistry - Retention loss of resin based fissure sealants - a valid predictor for clinical outcome? : reprint
|Article Title||Retention loss of resin based fissure sealants - a valid predictor for clinical outcome? : reprint|
|© Publisher:||Midentistry CC|
|Journal||Journal of Minimum Intervention in Dentistry|
|Affiliations||1 University of the Witwatersrand and 2 University of the Witwatersrand|
|Publication Date||Jan 2013|
|Pages||42 - 50|
|Keyword(s)||Diagnostic Odds ratio, Fissure sealant, Resin, Retention, Surrogate endpoint and Tooth caries|
Purpose : The hypothesis that retention loss of resin fissure sealants predicts caries manifestation more accurately than random values was tested.
Methods : Systematic reviews were checked and electronic databases searched for clinical trials. Trials reporting on the retention of resin sealants and caries occurrence in permanent molar teeth, with minimum 24-month follow-up period, were included. Extracted data: number of sealed teeth, number of teeth without completely retained sealants, number of sealed teeth with caries. The number of teeth with complete sealant retention and absence of carious lesions/cavities was calculated; the predictive outcomes: true/false positive; false/true negative were established. Random values were generated as control-data. Diagnostic Odds ratios (DOR) were computed and tested for statistical difference. Summary Receiver Operating Characteristic curves were plotted.
Results : 95 trials were found. Median DOR values were 1.21 and 0.28 for test- and control data, respectively. Wilcoxon test (z = 0.56; p = 0.58) and Sign test (z = 1.38; p = 0.17) results were statistically non-significant. The hypothesis was rejected.
Conclusions : Predictions based on the retention loss of resin sealants, regarding caries manifestation, was no more accurate than random guesses. Sealant retention loss appears not to be a valid predictor for clinical outcome.
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