n Journal of Minimum Intervention in Dentistry - In patients with comparable caries risk, do GIC fissure sealants protect better against caries then resin-based fissure sealants? [2008] : grey literature




[This document has been captured as part of the JMID-section for Grey- literature. Grey (or gray) literature refers to informally published written material that may be difficult to trace via conventional databases and/or journals as it is not formally published or is not widely accessible. However, Grey literature may still be an important source of information. Examples of grey literature include e.g.: patents, reports, working documents or unpublished manuscripts]

The systematic literature search identified 20 articles in compliance with the broad inclusion criteria. Of these, 11 articles were rejected due to insufficient internal validity. Nine articles were accepted, 3 of which were systematic reviews. Six trials were accepted for data extraction and further meta-analysis.Clinical heterogeneity was observed and articles grouped accordingly. The pooled odds ratio (OR) of 0.96 (CI 95% 0.62 - 1.50) indicate no large difference in the caries preventing effect between GIC and resin-based fissure sealants after 2 - 3 years. These results are consistent with other systematic reviews and 2 out of 9 trials not included into this meta-analysis due to aspects of internal validity. It is important to consider, that all trials accepted in this review investigated low-viscose GIC materials, only. New, high-viscose GIC materials have been introduced for sealing pits and fissures. Clinical application of these materials for fissure sealing differs from the application of low-viscose GIC. While the later are applied onto pits and fissures in thin consistency using a hand instrument, high viscose glass-ionomer materials are applied using pressure by gloved index finger coated with petroleum jelly. Such procedure may achieve deeper fissure penetration of the GIC material then the application of thin low-viscose GIC with a hand instrument. Such deeper fissure penetration may support its higher retention in pits and fissures, thus achieving a higher caries preventive effect. High quality randomized control trials are needed in order to compare the caries preventive effect of high viscose GIC fissure sealants in comparison to resin based fissure sealants. It is recommended that reporting of such studies should follow the CONSORT statement.


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