n Journal of Minimum Intervention in Dentistry - In patients with comparable caries risk, does GIC have a better cariostatic effect then amalgam? [2008] : grey literature

Volume 8, Issue 2
  • ISSN : 1998-801X



[This document has been captured as part of the JMID-section for Grey- literature. Grey (or gray) literature refers to informally published written material that may be difficult to trace via conventional databases and/or journals as it is not formally published or is not widely accessible. However, Grey literature may still be an important source of information. Examples of grey literature include e.g.: patents, reports, working documents or unpublished manuscripts]

The systematic literature search identified 12 articles in compliance with the broad inclusion criteria. Of these, 7 articles were rejected due to insufficient internal validity. Five articles were accepted for data extraction and further meta-analysis. Clinical heterogeneity was observed and articles grouped accordingly. Meta-analysis was conducted per group of articles. The estimated results suggest that GIC reduced the odds of caries incidence by 83% on primary teeth with multi-surface restorations (pooled OR = 1.73); 80% on primary teeth with single surface restoration (pooled OR = 2.02) and 80% on permanent teeth with single surface restorations (pooled OR = 2.00) of what they would have been if the teeth were restored with amalgam. These results are consistent with other trials not included into this meta-analysis due to aspects of internal validity. Further well designed RCTs are needed in order to confirm these results. It is recommended that reporting of such studies should follow the CONSORT statement.

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