oa South African Family Practice - Evidence for Zolpidem efficacy in brain damage : case study

Volume 47, Issue 3
  • ISSN : 2078-6190
  • E-ISSN: 2078-6204



Previous reports have shown that zolpidem could reverse semi-coma and improve cerebral perfusion after brain injury. Studies in animals have implicated omega 1 GABAergic action as reason for this improvement. Evidence for the efficacy of zolpidem in a wide range of brain pathology is reviewed here and the mechanism of zolpidem in brain injury is considered from the perspective of diaschisis and neurological dormancy after brain injury.

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