oa South African Family Practice - Evidence for Zolpidem efficacy in brain damage : case study
|Article Title||Evidence for Zolpidem efficacy in brain damage : case study|
|© Publisher:||Medpharm Publications|
|Journal||South African Family Practice|
|Author||R.P. Clauss and H.W. Nel|
|Publication Date||Apr 2005|
|Pages||49 - 50|
|Keyword(s)||Brain injury, Diaschisis, Dormancy and Zolpidem|
Previous reports have shown that zolpidem could reverse semi-coma and improve cerebral perfusion after brain injury. Studies in animals have implicated omega 1 GABAergic action as reason for this improvement. Evidence for the efficacy of zolpidem in a wide range of brain pathology is reviewed here and the mechanism of zolpidem in brain injury is considered from the perspective of diaschisis and neurological dormancy after brain injury.
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