oa South African Family Practice - Medifile : the role of statins in myopathy and their effects in osteoporosis
Extracted from text ... SA Fam Pract 2005;47(9) 14 October 2005; 19(9) EDITORIAL The safety of HMG-Co reductase-inhibitors (statins) is of great interest to clinicians, policy makers and the public. Although myopathy is well documented as a side-effect of the statins, the increase in numbers of patients using this drug class may cause more of these case symptoms to be reported.1 Apart from their effect on the lipid profile, statins have other clinical effects. Some of these effects eg improvement in endothelial function is relatively well documented, but other effects require further studies to prove clinical significance. Animal, in vitro and some observational studies ..
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