oa South African Family Practice - Male circumcision and HIV prevention : editorial

Volume 54, Issue 5
  • ISSN : 2078-6190
  • E-ISSN: 2078-6204



It is reported that there is grade I evidence that male circumcision reduces the risk of men acquiring human immunodeficiency virus (HIV) infection. This is based on three large randomised controlled trials (RCTs) on male circumcision that were undertaken in Africa, at Orange Farm, South Africa; Rakai, Uganda; and Kisumu, Kenya. The findings were published in and between 2007 and 2009. Over 10 000 men were circumcised at the three sites. The reported protective effect of male circumcision against HIV were Orange Farm (60%), Rakai (48%), and Kisumu (53%).

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