oa Southern African Journal of Epidemiology and Infection - Antimicrobial resistance in nosocomial infections



Bacterial and fungal resistance is an increasing threat to the successful treatment of nosocomial infections. As bacterial resistance continues to evolve, some pathogens that were once considered routine to treat have become resistant to almost all antimicrobial agents. In particular, the emergence of vancomycin resistance in and carbapenem resistance in strains of spp and is of great concern. Similarly, increased production and spread of extended spectrum beta-lactamases (ESBL) in Gram-negative bacilli like are worrisome.


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