oa Southern African Journal of Epidemiology and Infection - Methicillin-resistant (MRSA) : review



Community-associated methicillin-resistant (CA-MRSA) infections are defined as occurring in patients who have no association with the healthcare setting. CA-MRSA has emerged as a common cause of community infections in the US and are distinct from MRSA strains classically associated with healthcare-associated infections from genotypic and phenotypic perspectives. They are frequently susceptible to non-beta-lactam antimicrobials, express the SCC type IV or V gene and contain the Panton-Valentine leukocidin virulence factor. They most commonly cause mild skin infections, but have been associated with severe soft tissue infection and with necrotising pneumonia.


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