oa Southern African Journal of Epidemiology and Infection - Rotaviruses and emerging picornaviruses as aetiological agents of acute gastroenteritis : review
|Article Title||Rotaviruses and emerging picornaviruses as aetiological agents of acute gastroenteritis : review|
|© Publisher:||Medpharm Publications|
|Journal||Southern African Journal of Epidemiology and Infection|
|Affiliations||1 Rhodes University, 2 Rhodes University, 3 University of St Andrews, UK, 4 University of South Africa and 5 Agencia Espanola de Medicamentos y Productos Sanitarios (AEMPS), Spain|
|Publication Date||Jan 2012|
|Pages||141 - 148|
|Keyword(s)||Gastroenteritis, Picornavirus and Rotavirus|
It is estimated that up to 40% of acute gastroenteritis cases are undiagnosed. Rotavirus is a primary aetiological agent, so the introduction of vaccines into the national immunisation programmes of many countries, including South Africa, has shown promise in reducing the burden of disease and decreasing hospital admissions. Recently, several novel viruses have been isolated in association with gastroenteritis, although their epidemiology and clinical significance are poorly understood. This article highlights the importance of rotavirus in diarrhoeal disease. A review is provided of the molecular biology of emerging pathogens in the Picornavirus family.
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