oa Southern African Journal of Infectious Diseases - Factors associated with retreatment tuberculosis in Tshwane, South Africa : the role of tobacco smoking : brief report
|Article Title||Factors associated with retreatment tuberculosis in Tshwane, South Africa : the role of tobacco smoking : brief report|
|© Publisher:||Medpharm Publications|
|Journal||Southern African Journal of Infectious Diseases|
|Affiliations||1 University of Pretoria and 2 University of Limpopo|
|Publication Date||Jan 2014|
|Pages||87 - 90|
|Keyword(s)||Human immunodeficiency virus, Recurrent tuberculosis, Retreatment tuberculosis, Tobacco smoking and Tuberculosis relapse|
There is evidence from international studies that tobacco smoking increases the risk of tuberculosis recurrence through its effects on the immunological and barrier functions of the airways. In this cross-sectional study, the association between current tobacco smoking and retreatment tuberculosis was studied in a population of 1 926 South African tuberculosis patients with high human immunodeficiency virus (HIV) co-infection rates. Retreatment tuberculosis was more common in male and among HIV-positive participants currently on antiretroviral treatment, or with unknown antiretroviral treatment status. However, we did not find an association between smoking and retreatment tuberculosis. A longitudinal study is needed to confirm these findings.
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