oa Southern African Journal of Infectious Diseases - Low seroprevalence of antibodies to in blood donors in central Namibia : original research

Volume 29, Issue 3
  • ISSN : 2312-0053



Although emphasis has been placed on research relating to human immunodeficiency virus (HIV), tuberculosis and malaria, several researchers in Africa are focusing on other threats to human health, such as neglected tropical diseases. is a possible neglected tropical disease in Namibia, although the country has a diversity of climate, ranging from tropical in the north to semi-desert in the south. Except for one study in 1978, no recent studies have determined the burden of infection in Namibia. Three hundred and twelve convenience samples were collected from volunteer blood donors in central Namibia. Donors provided informed consent to participate in the study, and 5 ml blood was collected. Demographic information was collected by means of a questionnaire. Serum was analysed using Captia™ immunoglobulin G (Ig) G enzyme-linked immunosorbent assay (ELISA) kit. Only samples that tested positive or equivocal for IgG antibodies were then tested for IgM antibodies using Captia™ IgM ELISA kit. Of the 312 samples, 3 (0.961%) tested positive for IgG antibodies to . One sample (0.3%) tested positive for IgM antibodies to . These donors lived in urban areas in central Namibia and interacted regularly with animals, such as cats and dogs. The prevalence of antibodies to in Namibian blood donors was found to be considerably lower than that reported in other African countries, but comparable to that in a recent report from South Africa. It is notable that most of the donors lived in the arid central regions of Namibia, where the high altitude could also affect parasite survival.

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