oa Southern African Journal of Infectious Diseases - Hand-foot-and-mouth disease caused by coxsackievirus A6 in a patient infected with HIV : case report
|Article Title||Hand-foot-and-mouth disease caused by coxsackievirus A6 in a patient infected with HIV : case report|
|© Publisher:||Medpharm Publications|
|Journal||Southern African Journal of Infectious Diseases|
|Affiliations||1 University of Pretoria, 2 University of Pretoria, 3 University of Pretoria, 4 2National Health Laboratory Service Tshwane Academic Division, 5 Tshwane District Hospital and 6 Tshwane District Hospital|
|Publication Date||Jan 2015|
|Pages||67 - 69|
Hand, foot and mouth disease (HFMD) is common in children ≤ 5 years of age, and is mainly caused by enterovirus 71 and coxsackievirus A16 (CVA6). A 12-year-old boy on treatment for human immunodeficiency virus (HIV) presented to an HIV clinic with fever and a rash on the palms and soles. The syphilis test were negative. Enterovirus was identified from a stool sample by PCR and characterised as as coxsackievirus A6(CVA6). The patient completely recovered a week later. CVA6 has recently been associated with HFMD. This case highlights the significance of the laboratory confirmation of suspected HFMD cases and phylogenetic analysis of the identified virus.
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