oa Southern African Journal of Gynaecological Oncology - Endometrial sampling : a comparison between the Pipelle® endometrial sampler and the Endosampler® : original research

Volume 3, Issue 1
  • ISSN : 2074-2835
  • E-ISSN: 2220-105X



To compare the adequacy of endometrial sampling by the Endosampler® and the Pipelle®.

A total of 68 women were randomly assigned to submit to pre-hysterectomy endometrial sampling, either by the Endosampler® or the Pipelle®. The amount of endometrial tissue sampled was measured by calculating the percentage endometrium sampled by each of the two devices. Acceptance by the gynaecologist was measured on a linear scale.
The Endosampler® sampled significantly more endometrial tissue than the Pipelle® endometrial sampler (p-value = 0.03). Acceptance of the Endosampler® was better than that of the Pipelle® (p-value = 0.0005). With the use of the Pipelle®, three significant endometrial lesions were missed, including endometrial carcinoma in one instance.
The Endosampler® appears to be an easy-to-use device for endometrial sampling, with reliable diagnostic yield.

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