- A-Z Publications
- Southern African Journal of Gynaecological Oncology
- Previous Issues
- Volume 3, Issue 2, 2011
Southern African Journal of Gynaecological Oncology - Volume 3, Issue 2, 2011
Volume 3, Issue 2, 2011
Author Dominique LossignolSource: Southern African Journal of Gynaecological Oncology 3, pp 54 –57 (2011)More Less
Source: Southern African Journal of Gynaecological Oncology 3, pp 59 –64 (2011)More Less
We have an improved understanding of the pathophysiology and impact of perioperative pain. Targeted interventions to prevent and manage nociception are effective in improving patient satisfaction and surgical outcome. There are many alternatives, each with its own profile of benefits, risks and side-effects. A logical, stepwise, balanced approach utilising multiple modalities is effective, scales easily to the type of surgery, can adapt to changing requirements and resources, and promotes a seamless transition from theatre care to the ward and patient self-reliance.
Large loop excision of the transformation zone (LLETZ) : a pathology evaluation in the Limpopo province, South Africa : original researchSource: Southern African Journal of Gynaecological Oncology 3, pp 66 –69 (2011)More Less
Objective: To evaluate the cytological and histopathological concordance in large loop excision of the transformation zone (LLETZ) specimens, and the outcomes according to the characteristics of the excision margins.
Method: A prospective observational study of 413 consecutive cases of LLETZ performed for cytologically diagnosed high-grade squamous intraepithelial lesion (HGSIL) / cervical intraepithelial neoplasia (CIN) over a three-year period.
Results: The discordance rate between the initial cytological diagnosis and biopsy-proven HGSIL was 24.5%. The overall rate of margins believed to be clear and of severe thermal artifacts was 30.4% and 7.4% respectively. Pathology follow-up was available only in 83 (26.5%) of the 313 biopsy-confirmed HGSIL. The persistence or recurrence rate was 78.0%; 90.5% occurred among the cases where the margins were believed to be involved. In 20.5% the reported marginal status was discordant with follow-up surgical pathology.
Conclusion: Reporting marginal status has limited prognostic significance.
Investigating cervical cancer awareness : perceptions of the Female Cancer Programme in Mdantsane, South Africa : original researchSource: Southern African Journal of Gynaecological Oncology 3, pp 70 –72 (2011)More Less
Background: The Female Cancer Programme (FCP) is offering women visual inspection with acetic acid screening and if necessary, cryotherapy and medication. The aim of this study was to investigate the electiveness of the awareness campaign.
Method: This study took the form of a cross-sectional survey among women in Mdantsane. The questionnaires sought information about their knowledge of risk factors and symptoms, their opinions, information sources, reasons for participation and fears of cervical cancer screening.
Results: Five hundred and thirty-two questionnaires were collected. Sixty per cent had heard of cervical cancer and 74% of a Pap smear. Forty-three per cent thought the aim of screening was prevention. Forty-three per cent knew irregular blood loss and postcoital bleeding could be symptoms. Forty per cent got their information from a clinic. Fifty-one per cent would participate in a screening programme because of awareness. Thirty per cent did not have any fear of the screening. Eighty-four per cent thought the FCP is important for the future of Mdantsane. Forty per cent acquired their information about cervical cancer screening in a primary health clinic. The opinion about the screening program was positive.
Conclusion: Women in the Mdantsane community are unaware of risk factors and symptoms of cervical cancer. Women participate in cervical cancer screening programmes because of increasing awareness of the disease and the wish to stay healthy.
Author M. MoodleySource: Southern African Journal of Gynaecological Oncology 3, pp 74 –75 (2011)More Less
Radical trachelectomy is a well-described procedure for the preservation of fertility in women with early-stage cervical cancer. Experience of this procedure in an HIV (human immunodecience virus) -infected patient has not been reported. In this case, radical vaginal trachelectomy was performed in an HIV-infected patient with CD4 count of 350 cells/μl, after frozen section of the pelvic lymph nodes was performed. Frozen section of the pelvic lymph nodes was negative. Apart from a vaginal infection, the patient made good recovery with good oncological outcome. It seems, from this case, that radical vaginal trachelectomy in a patient with HIV infection is a feasible option when the immunity is reasonable.
A metastatic unclassified trophoblastic tumour with spontaneous bilateral pneumothoraces : case studySource: Southern African Journal of Gynaecological Oncology 3, pp 76 –78 (2011)More Less
Gestational trophoblastic disease (GTD) is a spectrum of diseases associated with pregnancy. Epithelioid trophoblastic tumour (ETT) is a rare neoplastic proliferation of the intermediate trophoblast that can be distinguished from choriocarcinoma. A 35-year-old female presented with persistent vaginal bleeding, raised beta human chorionic gondaotrophin (β-HCG) (13 175 IU/l) and, on ultrasound, what appeared to be a molar pregnancy. Microscopy and immunohistochemistry confirmed the diagnosis of ETT. Computed tomography (CT) scan confirmed bilateral small lung and liver metastases, and vaginal sonar, a single metastasis next to the urethra. Combination etoposide and cisplatin chemotherapy was completed. Restaging lung CT detected numerous cystic lesions and bilateral spontaneous pneumothoraces, caused by the rupture of subpleural cystic lesions. Bilateral underwater drains were inserted to address the complication of persistent spontaneous bilateral pneumothoraces, but she passed away. ETT is a rare malignant disorder associated with pregnancy. No standard treatment guidelines exist, and these patients need the efforts of a multidisciplinary team with experience in oncology.
SA Society of Clinical and Radiation Oncology (SASCRO) and SA Society of Medical Oncology (SASMO) : 15th National Congress, 24 - 27 August 2011, Sun City : congress abstractsSource: Southern African Journal of Gynaecological Oncology 3 (2011)More Less