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- Volume 4, Issue 2, 2012
Southern African Journal of Gynaecological Oncology - Volume 4, Issue 2, 2012
Volume 4, Issue 2, 2012
Author Leon SnymanSource: Southern African Journal of Gynaecological Oncology 4, pp 48 –49 (2012)More Less
Subspecialty training in gynaecological oncology in South Africa is a very young venture in the discipline of gynaecology. In 2008, the first candidate fulfilled the requirements for the College of Obstetricians and Gynaecologists of South Africa's subspecialty certificate in Gynaecological Oncology. As a subspecialty, gynaecological oncology adds significant value to the management and care of women who are diagnosed with gynaecological cancer, and enhances survival and treatment outcome. Therefore, there is no doubt that it is judicious to train gynaecological oncologists in South Africa.
Author P.F. WesselsSource: Southern African Journal of Gynaecological Oncology 4, pp 50 –54 (2012)More Less
The relationship between cancer and thrombosis has been known for many years. Thrombotic risk is increased in the patient with cancer, and the diagnosis of venous thromboembolism at the time that a malignancy presents influences patient outcome. Risk evaluation, prophylaxis and treatment of venous thromboembolism are practical issues that face doctors who are dealing with these patients.
A pilot study of two radiation fractionation regimens in patients with cancer of the cervix, who were HIV positive and not on antiretroviral therapy : original researchSource: Southern African Journal of Gynaecological Oncology 4, pp 55 –58 (2012)More Less
The Department of Radiation Oncology at the previously named Pretoria Academic Hospital (now the Steve Biko Hospital) undertook a pilot study between 2000 and 2001 of 20 patients who were human immunodeficiency virus-positive with locally advanced cancer of the cervix. At the time of the study, these patients were not on antiretroviral therapy, as per government policy. The patients were randomised into two arms. Six patients underwent a short palliative course of radiotherapy and 13 received a protracted and radical course of radiotherapy. One patient was lost to follow-up. Although the results were not statistically significant, the short course of palliative radiotherapy was adequate in terms of toxicity. As expected, the radical course was associated with a greater and more significant toxicity, because of the suppressed immune status of the participants.
Translation and validation of the EORTC QLQ-CX24 questionnaire into the indigenous African languages of isiXhosa and Afrikaans : original researchSource: Southern African Journal of Gynaecological Oncology 4, pp 59 –62 (2012)More Less
Objectives : Quality of life (QOL) assessment plays an important role in oncological clinical practice and research settings when evaluating treatment outcome. Cervical cancer remains a prevalent disease in South African women. The current study translated the European Organisation for Research and Treatment of Cancer (EORTC) cervical cancer module, QLQ-CX24, into isiXhosa and Afrikaans and validated the questionnaires.
Setting and subjects : The QLQ-CX24 was translated forwards into isiXhosa and Afrikaans and backwards into English, and then reconciled by four independent language practitioners. The translated version was completed by 15 isiXhosa- and 15 Afrikaans-speaking patients with cervical cancer. Cronbach's alpha coefficient, a measure of internal consistency of response, was calculated. The conversion validity was evaluated by assessing the correlation between each item and its scale. Discriminant validity was examined by comparing the correlation values of each item with other scales using Pearson's and Spearman's correlation coefficients.
Results : The translated isiXhosa and Afrikaans questionnaires demonstrated good conversion validity in the multi-item scales, with values of Cronbach's alpha coefficient ≥ 7. Discriminant validity was demonstrated in the single-item questions. Patients completed the questionnaires in less than 20 minutes.
Conclusion : The translated isiXhosa and Afrikaans versions of QLQ-CX24 were successfully translated and validated and is available for research and clinical use.
Source: Southern African Journal of Gynaecological Oncology 4, pp 63 –65 (2012)More Less
Cavernous haemangioma of the uterine cervix is extremely rare. Fewer than 50 have been reported cases to date. A nulliparous term woman presented with a sensation of "something coming out" of her introitus. The mass was found to be large, 8 cm in diameter, and arising from the uterine cervix. It was clinically diagnosed as a cervical fibroid. The mass was surgically resected and was sent for histopathological study. Grossly, it was a well-circumscribed, greyish-brown mass, measuring 6 x 7 x 8 cm. From the biopsy, the diagnosis that was made was cervical cavernous haemangioma. The patient later delivered a child by Caesarean section. Although cavernous haemangioma of the uterine cervix in pregnancy is a rare entity, it should be kept in mind as a differential diagnosis by clinicians.
Source: Southern African Journal of Gynaecological Oncology 4, pp 66 –68 (2012)More Less
Sclerosing stromal tumours (SSTs) are rare, benign, sex cord stromal tumours of the ovary. They affect women, who complain mainly of menstrual irregularity, in their second and third decades. We report a histologically confirmed case of a 23-year-old woman who presented with complaints of abdominal pain and irregular menstruation. She later underwent surgery when a pre-pathology workup raised the suspicion of a malignant tumour. It is imperative to consider the differential diagnosis of an SST of the ovary in a young woman with an ovarian tumour.
Source: Southern African Journal of Gynaecological Oncology 4, pp 69 –70 (2012)More Less
Serous tumours comprise one fourth of all ovarian tumours. Most occur in adults. We present a case of a 24-year-old woman with bilateral ovarian masses which appeared to be malignant on imaging and perioperatively. However, microscopy revealed benign serous cystadenofibromas of the ovaries. This case signifies the importance of microscopy in neoplasms that masquerade as malignant on imaging, perioperatively and grossly.