- A-Z Publications
- Southern African Journal of Gynaecological Oncology
- Previous Issues
- Volume 5, Issue 2, 2013
Southern African Journal of Gynaecological Oncology - Volume 5, Issue 2, 2013
Volume 5, Issue 2, 2013
Cancer in Africa : bridging science and humanity
The 9th International Conference of the African Organisation for Research and Training in Cancer : guest editorialAuthor Vikash SewramSource: Southern African Journal of Gynaecological Oncology 5, pp 39 –40 (2013)More Less
The African Organisation for Research and Training in Cancer (AORTIC) will be holding its 9th International Cancer Conference entitled "Cancer in Africa: Bridging Science and Humanity" at the Durban International Convention Centre from 21-24 November 2013. The AORTIC is a pan-African, bilingual, multi-disciplinary and non-governmental organisation that was formed in 1983 and dedicated to the promotion of cancer care and control in Africa. A conference is held biennially and after an exciting meeting in Cairo, Egypt in November 2011, we are proud to welcome the conference to the warm and sunny shores of Durban, South Africa. This year's theme "Cancer in Africa: Bridging Science and Humanity" invokes the essence and spirit of Ubuntu making us realize that science is no longer an isolated discipline, situated in the domain of academics. Science has entered the mainstream consciousness and as responsible individuals we must ensure that intellectual rigour is balanced by open mindedness, a breadth of culture and outlook. This is bound to ensure a world in which all individuals embrace one another's equality and are encouraged and inspired to use their inherent abilities to the fullest, and find their passion for, participate and contribute fully in, and benefit fairly from the prosperity that good health can bring.
Contextual quality of life of HIV-positive patients with cervical carcinoma at Tygerberg Hospital : original researchSource: Southern African Journal of Gynaecological Oncology 5, pp 41 –46 (2013)More Less
Objective : In South Africa, the majority of cervical carcinoma cases present when they are in the advanced stage. Concomitant HIV/AIDS further compromise patient health. Data on the impact of HIV/AIDS on the quality of life of cases with advanced cervical carcinoma are lacking. Contextual factors, e.g. patient's educational level and income, influence their experience of quality of life.
Design : A cross-sectional study was carried out on the quality of life of newly diagnosed cases of cervical carcinoma. Self-administered questionnaires were completed by patients and other contextual factors (e.g. age, educational level, socio-economic status and clinical information), were obtained from patient folders.
Setting and subjects : Newly diagnosed cases of invasive cervical carcinoma who presented at the Gynaecological Oncology Unit, Tyberberg Hospital, were included in the study. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaires (QLQ)-C30 version 3 and QLQ-CX24 were used.
Results : The total study cohort of 73 patients (HIV-negative and HIV-positive) had a median age of 49 (28.3-85.2 years). Of the patients, 7.1% had no formal education. The cohort had an unemployment rate of 41.5%, and 14.2% were pensioners. The marital state was predominantly single persons (31.4%), with a mean monthly income of R 1 373 (R0-14 000). Advanced stage of the disease was present in more than 50% of cases, and 32.2% were stage IIIb. Sixteen patients were HIV positive with an HIV-positive incidence of 22%.The comparative quality-of-life domains of HIV-negative and HIV-positive cases were statistically equal. Advanced stage, as a contextual factor, impacted significantly on a number of quality-of-life domains. These domains are amenable to medication.
Conclusion : HIV/AIDS did not adversely influence the quality of life of the newly diagnosed cervical carcinoma cases. In this regard, stage of disease had a significant impact on the domains of pain, insomnia, nausea and vomiting, appetite loss and constipation. These aspects are amenable to treatment. Cognitive function was adversely influenced by increasing age, poor education and a low monthly income. When giving support to patients with regard to enhancing their quality of life, this should be recognised and communicated to them.
Consensus recommendations for the prevention of cervical cancer in sub-Saharan Africa : consensus paperSource: Southern African Journal of Gynaecological Oncology 5, pp 47 –57 (2013)More Less
Cervical cancer is the second most common cancer and the leading cause of cancer-related death in women in sub-Saharan Africa. It is estimated that more than 200 million females older than 15 years are at risk in this region. This paper highlights the current burden of cervical cancer in sub-Saharan Africa, reviews the latest clinical data on primary prevention, outlines challenges in the region, and offers potential solutions to these barriers. Based on these factors, clinical recommendations for the prevention of cervical cancer from the sub-Saharan African Cervical Cancer Working Group expert panel are presented.
Prolonged survival after laparoscopic splenectomy for recurrent ovarian cancer and no adjuvant therapy : a report and review of the literature : case studySource: Southern African Journal of Gynaecological Oncology 5, pp 58 –61 (2013)More Less
Isolated splenic recurrent ovarian cancer is uncommon and may present remotely from initial surgery and chemotherapy. Surgical excision remains the treatment of choice for this condition. While widely used, the role of adjuvant therapy in this situation is unclear. We present a case of isolated recurrent splenic ovarian cancer treated with surgery and no adjuvant therapy, and review the literature on management of this condition.
Schistosoma haematobium in a human immunodeficiency virus-positive patient with cancer of the cervix : case studySource: Southern African Journal of Gynaecological Oncology 5, pp 62 –63 (2013)More Less
Schistosomiasis of the genital tract is uncommon, but is not infrequently encountered in Africa. Usually it will involve the rectum or the bladder, but genital tract involvement has been reported in areas with a high prevalence of the disease. Furthermore, schistosomiasis may increase the risk of human immunodeficiency virus (HIV) infection. It has also been postulated that schistosomiasis may be a risk factor for the development of cervical cancer.
Source: Southern African Journal of Gynaecological Oncology 5, pp 64 –67 (2013)More Less
Endometrial cancer is the seventh most common gynecological malignancy. The standard of care is surgery, followed by further treatment based on the surgical and histological findings. Usually, recurrences (80%) from endometrial cancer are seen within three years of hysterectomy and late recurrences are rare. The incidence of isolated lung recurrences is approximately 2.3-7%. This is a case report of endometrial cancer with locoregional and distant recurrence.