oa SA Pharmaceutical Journal - Menopause and hormone replacement therapy : clinical



The menopause is an ideal time to make a comprehensive health review.

Decisions about HRT rest with each woman after consultation with her doctor.
Decision-making requires an individual 'medical judgement'.
The absolute and attributable risks and benefits of HRT as well as the relative risks must be considered.
Statistical significance does not always imply clinical significance.
Conclusions from relatively older groups of women in WHI trials do not necessarily apply to younger postmenopausal women.
Younger postmenopausal women have more distressing menopausal symptoms and much lower absolute risks.
For many women the immediate need for relief of menopausal symptoms outweighs consideration of both long-term risks and benefits.
Age, severity of symptoms, medical status and history are key factors in decision-making.
HRT is the most effective treatment for vasomotor symptoms and enables many women to live full and active lives without embarrassment or distress.


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