oa SA Pharmaceutical Journal - Drug alert

Volume 73, Issue 7
  • ISSN : 2221-5875
  • E-ISSN: 2220-1017



Extracted from text ... Drug ALERT Discontinuation of aspirin - A trigger for stroke? Aspirin, because of its antithrombotic effect, is widely used for the prevention of ischaemic vascular disease. It is also often discontinued before surgery because it may prolong bleeding time and increase blood loss. Anecdotal evidence indicates that strokes can occur when patients stop either warfarin or aspirin before surgery. It is not clear whether this apparent association is coincidental, a result of increased coagulation from the surgery or caused by the discontinuation of the antithrombotic medication. A study was conducted to determine whether discontinuation of aspirin is a risk factor ..

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