oa SA Pharmaceutical Journal - Prescribing combined oral contraceptives for women with pre-existing medical conditions : clinical

Volume 74, Issue 1
  • ISSN : 2221-5875
  • E-ISSN: 2220-1017



COCs are safe and effective when used correctly and consistently.

COCs have non-contraceptive benefits, e.g. antiandrogen.
If the woman has significant cardiovascular risk factors, alternative methods should be considered.
The risk of venous thromboembolism is lower with COC use than with pregnancy.
Dual protection is recommended if there is risk of transmission of sexually transmitted infections including HIV.
If a woman is taking medication which lowers the efficacy of the low-dose COC (< 35 µg EE) an alternative or additional method is recommended.
For missed pills, apply the two for twenty and three for thirty rule.

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