oa SA Pharmaceutical Journal - Challenges in TB treatment in South Africa : forum

Volume 74, Issue 10
  • ISSN : 2221-5875
  • E-ISSN: 2220-1017



At no time in recent history has tuberculosis (TB) been as great a concern as it is today. Despite highly effective drugs, morbidity and mortality due to are increasing and are being fuelled by the HIV epidemic. In 2005 the World Health Organisation (WHO) highlighted the fact that South Africa, largely as a result of HIV, was one of the 22 high burden TB countries and that it had the fifth highest number of notified TB cases in the world. A serious aspect of the TB problem has been the emergence of drug resistant (particularly multidrug-resistant) tuberculosis, which poses a threat both to individual patients and communities. Further to this, the WHO has declared TB an emergency in Africa, calling for urgent and extraordinary action.

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