oa SA Pharmaceutical Journal - New product focus - Adacel Quadra : drug info
There has been a resurgence in the incidence of pertussis in several countries. There has also been a shift in the age distribution of pertussis, with dramatic increases being reported among adolescents and adults. It appears, therefore, that immunity to pertussis, whether acquired from natural infection during childhood or whether acquired from routine infant immunisation, may not be lifelong. Indeed, it has been shown that the duration of protection from both whole cell and acellular pertussis vaccine is six years, while natural infection may provide protection for up to 15 years.
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