oa SA Pharmaceutical Journal - Hormone therapy in postmenopausal women - an update : review

Volume 76, Issue 8
  • ISSN : 2221-5875
  • E-ISSN: 2220-1017



The risks of hormone therapy have received much attention in the medical and popular press. However, current evidence shows that hormone therapy given to symptomatic, otherwise healthy, peri- and postmenopausal women under 60 years of age can be safe and effective. The main indication for HT should be for symptom relief. Hormone therapy must be individualised so that the immediate symptoms are managed and the potential risks may be reduced. Early initiation of hormone therapy in symptomatic patients enables both relief of menopausal symptoms and protects against the consequences of oestrogen deficiency, such as osteoporosis. The beneficial effects of hormone therapy can be achieved at lower doses, allowing the maintenance of benefits of hormone therapy while side effects may be minimised.

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