oa SA Pharmaceutical Journal - Rotavirus infection : review

Volume 77, Issue 4
  • ISSN : 2221-5875
  • E-ISSN: 2220-1017



Rotavirus gastroenteritis is a common cause of severe infection throughout the world, even in countries with good hygiene and sanitation measures. Rotavirus infection is characterised by sudden onset of watery diarrhoea, fever and vomiting. Although the infection is usually mild and self-limiting, it can lead to severe dehydration with electrolyte imbalances followed by death. Prevention of rotavirus infections can best be achieved through vaccination. The rotavirus vaccine has been shown to be a safe and effective vaccine. The World Health Organization recommends that rotavirus vaccination be incorporated into all national immunisation schedules.

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