oa SA Pharmaceutical Journal - Dysthymia : more than "minor" depression : review

Volume 78, Issue 3
  • ISSN : 2221-5875
  • E-ISSN: 2220-1017



Dysthymia is an under-diagnosed mood spectrum disorder that is almost as common as major depression and, if left untreated, has a chronic course which can impact negatively on a patient's quality of life. Whilst symptoms are not as numerous or severe as in major depressive disorder (MDD), morbidity associated with dysthymia can be serious owing to the long duration of the distressing syndrome. Consistently depressed mood can lead to impairment in workplace functioning, as well as compromised management of interpersonal, marital and familial relationships. Optimal management involves a combination of pharmacological treatment with antidepressant medications (e.g. selective serotonin reuptake inhibitors) and various forms of psychotherapy.

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