oa SA Pharmaceutical Journal - Chronic obstructive pulmonary disease and antibiotic use : review

Volume 79, Issue 5
  • ISSN : 2221-5875
  • E-ISSN: 2220-1017



Chronic obstructive pulmonary disease (COPD) is a disease state resulting from an abnormal inflammatory response of the lungs to irritant particles and gases, with resultant progressive airflow limitation, that is partially reversible. It is associated with lung hyperinflation and systemic effects, such as chronic cough, exertional dyspnoea, expectoration, and wheezing. COPD causes physical impairment, debility, and reduced quality of life. Symptoms such as coughing or wheezing can be treated with medication. Respiratory infections should be treated with antibiotics, if appropriate. The pathological correlates are chronic bronchitis and emphysema.

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