oa SA Pharmaceutical Journal - What's the latest on sulphonylureas in the management of type 2 diabetes? : review
|Article Title||What's the latest on sulphonylureas in the management of type 2 diabetes? : review|
|© Publisher:||Medpharm Publications|
|Journal||SA Pharmaceutical Journal|
|Publication Date||Jun 2013|
|Pages||12 - 14|
|Keyword(s)||Chlorpropamide, Glibenclamide, Gliclazide, Glimepiride, Glipizide, Sulphonylureas and Type 2 diabetes|
Sulphonylureas act by binding to sulphonylurea receptors and stimulating insulin secretion from pancreatic beta cells. This class of oral hypoglycaemic agents is still widely used in the management of type 2 diabetes in patients where lifestyle changes alone are insufficient. Although the older-generation sulphonylureas no longer have a place in therapy, the newer-generation sulphonylureas are a widely recognised choice, either as monotherapy, or in combination with insulin and/or other oral hypoglycaemic agents.
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