oa SA Pharmaceutical Journal - An approach to gastroprotective analgesia : review

Volume 80, Issue 6
  • ISSN : 2221-5875
  • E-ISSN: 2220-1017



As a class, nonsteroidal anti-inflammatory drugs (NSAIDs) comprise traditional nonselective NSAIDs and selective cyclo-oxygenase-2 inhibitors. NSAIDs are among the most widely used medications in the world because of their demonstrated efficacy in reducing pain,fever and inflammation. NSAIDs have been used for the management of a variety of clinical disorders, including rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout, musculoskeletal injuries, dysmenorrhoea, headaches and dental pain. However, the gastrointestinal toxicity associated with nonselective NSAIDs may cause side-effects that range from mild dyspepsia to gastrointestinal ulceration.

Loading full text...

Full text loading...


Article metrics loading...


This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error