SA Pharmaceutical Journal - Volume 80, Issue 8, 2013
Volume 80, Issue 8, 2013
Author Johann KrugerSource: SA Pharmaceutical Journal 80 (2013)More Less
We already know that drug design has moved to new levels, where it is a process that is driven by innovation and technological breakthroughs that involve a combination of advanced experimental and computational methods. A broad variety of medicinal chemistry approaches can be used to identify hits, the generation of leads, as well as to accelerate the optimisation of leads into drug candidates. The quantitative structure-activity relationship formalisms are among the most important strategies that can be applied to successfully design new molecules, according to a paper that was published by Andrade et al on PubMed.
Source: SA Pharmaceutical Journal 80, pp 8 –11 (2013)More Less
Pharmacists' indemnity concerns : Charlie Cawood
Prominent insurer repudiates a dispensing error claim: potential cost to the pharmacist circa R1.6 million : Charles Skinner
Investing in our future: The Foundation for Pharmaceutical Education
Welcoming new members
Pharmacists elected to the SAPC
Author Ronelle CoetzerSource: SA Pharmaceutical Journal 80, pp 12 –15 (2013)More Less
Although other forms of drug delivery are increasing in popularity, currently approximately 74% of medicine is administered orally. Transdermal drug delivery systems (TDDS) are dosage forms that involve the transportation of drugs across the different skin layers for a therapeutic effect. Currently, several transdermal patches are available for pain relief. This review will discuss the different components of the TDDS, as well as the various types of transdermal patches that are available in South Africa.
Author Lee BakerSource: SA Pharmaceutical Journal 80, pp 16 –19 (2013)More Less
Rabies is one of the oldest infectious diseases known to man. It is always fatal once symptoms have started, but can be prevented if appropriate wound treatment and post-exposure prophylaxis is given. Animal rabies is endemic in South Africa and dog bites are responsible for most human cases. Although a number of cases are confirmed, many are not, as they occur in the rural areas or may be misdiagnosed. Rabies immunoglobulin and effective vaccines are available in South Africa. A pre-exposure vaccination is recommended for those who are at risk of being exposed to rabies. Post-exposure vaccination is life-saving for those who have been exposed to rabies. This article gives insight into when to administer the vaccine and immunoglobulin and the appropriate schedules.
Author D. RodsethSource: SA Pharmaceutical Journal 80, pp 20 –23 (2013)More Less
Bipolar disorder is a complex mood disorder, both in terms of the diagnosis and management. It can have devastating consequences if inappropriately managed, but good management can allow sufferers to lead normal lives. While it is in the general realm of specialist diagnosis and care, general practitioners can play an important role in early identification of the disorder and long-term management, in shared care with the psychiatrist.
Author Gail MkeleSource: SA Pharmaceutical Journal 80, pp 24 –26 (2013)More Less
Bisphosphonates are a class of medicine used to treat bone disorders and malignancies associated with an increased risk of fractures. Their primary mechanism of action is inhibition of osteoclastic bone resorption. Over the past few years, a number of bisphosphonates and generics thereof have become available on the market. An increasing body of literature has suggested that their use may be associated with a variety of adverse effects. In this article, the pharmacology, mechanism of action and safety profile of bisphosphonates will be reviewed.
Source: SA Pharmaceutical Journal 80, pp 28 –29 (2013)More Less
Source: SA Pharmaceutical Journal 80, pp 30 –34 (2013)More Less
Allergies are among the most common chronic conditions worldwide. The severity of allergies varies from person to person and can range from minor irritation to life-threatening anaphylactic reactions. The pharmacist is in an ideal situation to promote preventative measures for allergy sufferers. The following questions and answers will help to assist the pharmacist in providing patients who suffer from allergies with much needed information on the subject.
Generic substitution and the Consumer Protection Act : a pharmacist's perspective : practice mattersSource: SA Pharmaceutical Journal 80, pp 35 –38 (2013)More Less
A patient who presents a prescription to a pharmacist for dispensing can expect to enjoy the rights and protection afforded to him under the Consumer Protection Act with regard to choice, informed consent and the safety of the supplied goods. The pharmacist is obliged to provide safe, quality medicine in accordance with the Medicines and Related Substances Act, and is ethically bound to exercise sound judgement and professional expertise in accordance with Good Pharmacy Practice (GPP) rules to ensure the maximum safety and efficacy of the prescribed treatment. In exploring this transfer of medicine and knowledge from pharmacist to patient, I wish to demonstrate that such transactions are not as simple as they might appear to be, especially when generic substitution is involved.
Author Shirley-Anne BoschmansSource: SA Pharmaceutical Journal 80, pp 39 –40 (2013)More Less
Source: SA Pharmaceutical Journal 80, pp 41 –43 (2013)More Less
More focus has been placed on patient counselling in recent times. It is not just required by the Pharmacy Act, but is also a responsibility in terms of the Consumer Protection Act and the National Core Standards. Effective counselling is paramount in a society that expects and demands swift, quality service delivery. The majority of patients may be uneducated, which could lead to inappropriate or incorrect use of medication. In a government setting, patient counselling is mostly carried out by post-basic pharmacist's assistants at hospital and clinic level.
Author Stephan MollerSource: SA Pharmaceutical Journal 80 (2013)More Less
The South African Association of Hospital and Institutional Pharmacists (SAAHIP) fraternity expects service delivery beyond reproach. And for good measure, as SAAHIP members, they provide service as a matter of fact, every day of their lives. Therefore, it is about time that we share in more definitive terms what we, as SAAHIP leaders, endeavour to accomplish for our members in particular, and for hospital and institutional pharmacists in general.