oa SA Pharmaceutical Journal - Paediatric antiretroviral guidelines at a glance : review

Volume 81, Issue 2
  • ISSN : 2221-5875
  • E-ISSN: 2220-1017



Dealing with the challenges of human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) continues to be a major global and regional health priority. An estimated 3.4-million children were living with HIV by the end of 2011. The majority of these affected children reside in the developing world, with approximately 91% in sub-Saharan Africa. Most of these children acquire HIV from their HIV-infected mothers during pregnancy, birth or breastfeeding. With efficacious interventions, the risk of mother-to-child HIV transmission may be reduced. Advances in treatment and prevention of HIV infection have resulted in dramatic improvements in the morbidity and mortality of HIV-infected children.

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