oa SA Pharmaceutical Journal - Hormone replacement therapy : an update : review

Volume 81, Issue 6
  • ISSN : 2221-5875
  • E-ISSN: 2220-1017



There has been much controversy regarding the use of hormone replacement therapy (HRT), also known as menopausal hormone therapy, in the past decade. Evidence from clinical trials challenged previously accepted recommendations for HRT in menopausal women, especially with regard to aspects of safety and disease prevention. This led to much confusion for clinicians, as well as patients, with many symptomatic menopausal women unnecessarily being denied HRT. Different reviews of published clinical data have necessitated that menopausal societies around the world reach a global consensus on the core recommendations regarding HRT. Consensus has now been reached and a global consensus statement on menopausal hormone therapy was published in 2013 by the International Menopause Society. This article will provide a summary of the key highlights from the consensus statement.

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