oa SA Pharmaceutical Journal - A review of epileptic drugs : review

Volume 81, Issue 7
  • ISSN : 2221-5875
  • E-ISSN: 2220-1017



Epilepsy is one of the most common neurological disorders in South Africa. Approximately 20-30% of patients with epilepsy have physically, socially and medically disabling seizure disorders. Such patients are at an increased risk of cognitive disorders, depression, physical trauma and sudden death. The management of epilepsy focuses on controlling seizures, avoiding treatment-related side-effects and maintaining or restoring quality of life. Two thirds of people with active epilepsy control their epilepsy satisfactorily with antiepileptic drugs. Other treatment approaches include surgery, if treatment with antiepileptic drugs is ineffective. Optimal management improves health-related outcomes and may also help to minimise other, often detrimental, impacts on social, educational and employment activity.

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