oa SA Pharmaceutical Journal - Hypertension : a review of antihypertensive medication, past and present : review

Volume 82, Issue 2
  • ISSN : 2221-5875
  • E-ISSN: 2220-1017



This article provides an overview of the changes that have taken place in the diagnosis and management of hypertension over the past decade. Hypertension remains a very common condition seen in South Africa. The approach to the management of hypertension includes necessary lifestyle modifications and a decisive, stepwise escalation process in the pharmacotherapeutic management thereof. Thiazide diuretics are still being promoted by most guidelines to be the initial (first-line) drug of choice, with the addition of other suitable antihypertensive agents, if necessary, and according to any relevant co-morbid conditions.

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